Valeriya Malysheva


I use a combination of wet-lab and computational approaches to study promoter-enhancer interactions in the context of gene regulatory networks.

Helen Ray-Jones


I use population genetics approaches to understand the logic of enhancer-promoter interactions.

Monica Della Rosa

PhD student

Monica is investigating the logic of gene regulation by enhancer elements in human pluripotent cells.

Pavel Artmemov

PhD student

Namrata Gogineni

MSc student

Namrata is working with Pavel on computational methods to predict the effect of enhancers on gene expression.

Mikhail Spivakov

Group Leader

I am interested in the logic and robustness of gene regulation. I am also interested in keeping the group happy and motivated.

More about Mikhail

Group Alumni

Joseph Ellaway

MSc student

Joseph worked with Pavel on the computational methods to predict the effect of enhancers on gene expression (a project later picked up by Namrata). He moved on to continue his Masters course.

Vanessa Tan

BSc student

Vanessa worked with Helen on the chromatin properties of genetic variants and is now back home in Singapore to continue her education.

Michiel Thiecke

PhD student

    Michiel worked on the effects of cohesin and CTCF on promoter-enhancer interactions. He has moved on to a Senior Computational Biologist position at Enhanc3D Genomics Ltd.

    Lina Dobnikar

    PhD student

      Lina led single-cell genomics analysis of vascular lineage plasticity. She has moved on to a Staff Bioinformatician position at CeMM, Vienna.

      Emma Yang

      MSc student

        Emma did her Masters project in our group, looking at the molecular underpinnings of immune traits, including COVID susceptibility. She moved on to start her PhD studies in Edinburgh after a gap year.

        Anna Litovskikh

        BSc student

          Anna did her summer internship and 3rd year project with us, working with Helen to study the chromatin properties of genetic variants.

          Carmen Petitjean

          BSc student

            Carmen did her 3rd year project with us, working with Valeriya on the enhancer-promoter interaction detection.

            Mirko Celii

            Visting postdoc

              Mirko was visiting from Valerio Orlando’s lab to study the nuclear dynamics of muscle cell differentiation.

              Will Orchard

              Visting student

                Will worked on the chicdiff pipeline before going back to continue his studies at Cambridge University.

                Jo Mitchelmore

                PhD student

                  Jo worked on the transcriptional effects of variation in transcription factor binding. She has moved on to a Data Scientist position at Novartis Institutes of Biomedical Research in Basel.

                  Jonathan Cairns

                  Postdoc (jointly with Peter Fraser group at Nuclear Dynamics ISP)

                    Jonathan worked on the Chicago pipeline. He moved to become a Senior Research Statistician at AstraZeneca.

                    Hashem Koohy

                    Postdoc (jointly with Nuclear Dynamics ISP)

                      Hashem worked on the cis-regulatory features of V(D)J recombination. He moved to start his own group at Oxford University’s Radcliffe Department of Medicine.

                      Paula Freire Pritchett


                        Paula worked on the Chicago pipeline and the rewiring of enhancer-promoter interactions upon human ES cell differentiation. She moved to MRC LMB as a founding member of the core bioinformatics facility.

                        Pawel Bednarz

                        Visiting student

                          Pawel moved back to Poland to finish his PhD at Warsaw University.

                          Phoebe Oldach

                          MPhil student

                            Phoebe moved back to the US, and then again on the island to do a PhD at Oxford.

                            Sunghee Park

                            Visiting professor

                              Sunghee is now back at Soongsil University in Seoul.

                              Qian Gao

                              Postdoc (jointly with Jon Houseley group at Epigenetics ISP)

                                Qian joined Adaptimmune as a bioinformatics scientist.

                                Erin Oerton

                                Rotation PhD student

                                  Erin moved on to do a PhD in Andreas Bender’s group at Cambridge University’s Department of Chemistry

                                  Manuela Zanda

                                  Visiting postdoc

                                    Manuela was staying with us in 2013 as part of our collaboration with her main lab at UCL led by Vincent Plagnol. Manuela has moved on to become a data scientist at ARM.