We aim to decipher the ground rules of gene regulation and establish their functional interplay in biological phenomena involving global changes in phenotype, such as in cell differentiation and activation. Our current focus is on the role of non-coding DNA elements such as enhancers in integrating and transmitting gene regulatory information.
MRC LMS is part of Imperial College’s Institute of Clinical Sciences (ICS) and is based on the Hammersmith Hospital campus, opening up many exciting opportunities for collaborations across disciplines.
A few people in our lab – including Helen, Valeriya and Emma, helped by Michiel who is now employed by our spinout compa…
Michiel’s paper on the effects of architectural protein depletion on promoter interactions is out in Cell Reports. It ha…